Sr-containing hydroxyapatite: morphologies of HA crystals and bioactivity on osteoblast cells

► The addition of Sr influences the structure of HA. ► The addition of Sr causes a decrease in the crystallinity degree of HA materials. ► The presence of Sr in the HA composition increases the reactivity of the materials. ► Sr-substituted HA and SrCl2 do not produce any cytotoxic effect in MG-63 cells. ► Sr-HA increases the proliferation of osteoblast cells.