Acrylic formulations containing bioactive and biodegradable fillers to be used as bone cements: Properties and biocompatibility assessment

► It was evidenced that the PHBV polymer made the cement more resistant. ► Concerning PHB a reduction in its degree of crystallization was verified. ► The PHB-containing cements led to larger amounts of residual monomer. ► The cement filled with PHBV took up more water than the PHB cement after 60 days. ► PHBV cements promoted a more developed and well-organized osteoblastic cell layer.