Study of drug-eluting coating on metal coronary stent

► How the spray parameters control the quality of coating was systematically studied. ► PEG increased the coating deformation ability and affected the drug-eluting profile. ► Proper increase of polymer/drug ratio could avoid the drug burst releasing. ► Uniform surface, good deformation and stabilized drug release profiles were obtained. ► Relevance between spray process and surface, deformation, drug release was studied.