کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10615064 | 987216 | 2005 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Immobilization of chitosan gel with cross-linking reagent on PNIPAAm gel/PP nonwoven composites surface
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
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چکیده انگلیسی
This study was to immobilize chitosan (CS), which is a biodegradable and antibacterial polymer, on poly(N-isopropylacrylamide) (PNIPAAm) gel/polypropylene (PP) nonwoven composites surface for wound dressing applications. PP nonwoven has been extensively used due to its porosity, allowing ventilation, high surface area and excellent mechanical properties. However, the hydrophobic surface of PP nonwoven limits its applications; in this study, we used the plasma-activation treatment and subsequently UV-light graft polymerization of NIPAAm gel to improve its hydrophilicity. Chitosan was immobilized onto PNIPAAm gel/PP nonwoven composites surface using the cross-linking agent, glutaraldehyde (GA). This complex was characterized by scanning electron microscopy (SEM). The results indicated that the wettability of the composite was improved after plasma treatment and photo-induced graft polymerization and chitosan was successfully immobilized onto the surface of PNIPAAm gel/PP nonwoven composites through cross-linking process. Finally, the preliminary result shows that chitosan hydrogels displayed antibacterial ability to Escherichia coli and Staphylococcus aureus. The (3-(4, 5-dimethylthiazolyl-2)-2, 5-diphenyltetrazolium bromide) (MTT) method indicated that the porous chitosan sponge exhibited good biocompatibility to fibroblast cells.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Materials Science and Engineering: C - Volume 25, Issue 4, June 2005, Pages 472-478
Journal: Materials Science and Engineering: C - Volume 25, Issue 4, June 2005, Pages 472-478
نویسندگان
Ko-Shao Chen, Yuan-An Ku, Chi-Han Lee, Hong-Ru Lin, Feng-Huei Lin, Tim-Mo Chen,