کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10630947 | 991464 | 2016 | 21 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Biosilicate® - A multipurpose, highly bioactive glass-ceramic. In vitro, in vivo and clinical trials
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
سرامیک و کامپوزیت
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
In this review we critically analyze 28 theses and dissertations and over 30 scientific papers that tested Biosilicate®, a highly bioactive glass-ceramic, in a number of applications throughout the past 20Â years. Biosilicate® presents a combination of positive features for bone tissue regeneration: it is highly bioactive, osteoconductive, osteoinductive, non-cytotoxic, non-genotoxic and has antibacterial properties. In addition, in the monolithic form, it is quite strong and tough. Its in vitro bioactivity is similar to that of the gold standard Bioglass 45S5. Biosilicate® has shown to be a very versatile, multipurpose biomaterial. It can be applied in powder, monolithic and 3D scaffold forms that could be easily machined during surgical procedures. This material has been successfully tested in a number of in vitro, in vivo and clinical studies, and several trials are ongoing. Biosilicate® is indeed a great option for a wide range of tissue engineering applications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Non-Crystalline Solids - Volume 432, Part A, 15 January 2016, Pages 90-110
Journal: Journal of Non-Crystalline Solids - Volume 432, Part A, 15 January 2016, Pages 90-110
نویسندگان
Murilo C. Crovace, Marina T. Souza, Clever R. Chinaglia, Oscar Peitl, Edgar D. Zanotto,