Glomerular disease

Glomerular disease has a variety of presentations that may be commonly encountered in clinical practice. The list of potential causes is extensive, but by focusing on the clinical presentation a swifter diagnosis may be reached. This article focuses on how basic investigations are used in everyday practice to inform an eventual diagnosis. Often, therapies for glomerular dysfunction are not disease-specific but rather directed against recognized risk factors for progression of chronic kidney disease. These are discussed, and safeguards for treating individuals with glomerular disease are described.