کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10730493 1042558 2011 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
One-pot production of 18F-biotin by conjugation with 18F-FDG for pre-targeted imaging: Synthesis and radio-labelling of a PEGylated precursor
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم تشعشع
پیش نمایش صفحه اول مقاله
One-pot production of 18F-biotin by conjugation with 18F-FDG for pre-targeted imaging: Synthesis and radio-labelling of a PEGylated precursor
چکیده انگلیسی
The biotin-avidin affinity system is exploited in pre-targeted imaging using avidin-conjugated antibodies. 18F-FDG is available at all PET centres. 18F-FDG forms oximes by reaction with oxyamine. Herein we describe the synthesis of oxyamine-funtionalised biotin, its 18F-labelling by conjugation with 18F-FDG and confirm its ability to interact with avidin.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 69, Issue 2, February 2011, Pages 418-422
نویسندگان
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