کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10730502 1042558 2011 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
'2+1' Tricarbonyltechnetium(I)/tricarbonylrhenium(I) mixed-ligand complexes with methyl thiosalicylate and isocyanide ligands as potential precursors of radiopharmaceuticals
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم تشعشع
پیش نمایش صفحه اول مقاله
'2+1' Tricarbonyltechnetium(I)/tricarbonylrhenium(I) mixed-ligand complexes with methyl thiosalicylate and isocyanide ligands as potential precursors of radiopharmaceuticals
چکیده انگلیسی
The complexes of [99mTc]-tricarbonyltechnetium(I) and [188Re]-tricarbonylrhenium(I), of the '2+1' type, with methyl thiosalicylate as an anionic bidentate ligand and with either tert-butyl 3-isocyanopropionate or glycine-glycine-tyrosine 4-isocyanobutyrate as monodentate ligands, have been prepared on the n.c.a. scale. The complexes exhibit different lipophilicity and high stability in neutral aqueous solutions. Based on the results of the challenge experiment with histidine, cysteine and glutathione the studied complexes might be considered to be promising models for radiopharmaceutical precursors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Radiation and Isotopes - Volume 69, Issue 2, February 2011, Pages 436-442
نویسندگان
, , , ,