کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10754 701 2007 14 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The effect of positively charged plasma polymerization on initial osteoblastic focal adhesion on titanium surfaces
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
The effect of positively charged plasma polymerization on initial osteoblastic focal adhesion on titanium surfaces
چکیده انگلیسی

The crucial factor of metal implant ingrowth in the bone is the rapid cellular acceptance. Therefore, the knowledge about additionally used adhesion mechanisms of osteoblasts, like their negatively charged hyaluronan coat, generates new surface functionalization strategies. Here, titanium was coated with a very thin, adherent, cross-linked, pinhole- and additive-free allylamine plasma polymer layer (PPAAm) resistant to hydrolysis and delamination and equipped with a high density of positively charged amino groups. This plasma polymer-functionalization of titanium is advantageous concerning osteoblastic focal adhesion formation as vinculin and paxillin, actin cytoskeleton development and, in consequence in differentiated cell functions, compared to a pure titanium surface—but similar such as the collagen I bonded surface via a polyethylenglycol-diacid (PEG DA)-spacer.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomaterials - Volume 28, Issue 30, October 2007, Pages 4521–4534
نویسندگان
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