کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1079465 1486694 2012 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Course of Life Into Adulthood of Patients With Biliary Atresia: The Achievement of Developmental Milestones in a Nationwide Cohort
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Course of Life Into Adulthood of Patients With Biliary Atresia: The Achievement of Developmental Milestones in a Nationwide Cohort
چکیده انگلیسی

PurposeTo investigate the course of life of young adults diagnosed with biliary atresia (BA) in infancy by comparing patients who did and did not underwent transplantation with an age-matched Dutch reference group.MethodsAll patients from the Dutch BA registry, aged >18 years, were invited to complete the course of life questionnaire.ResultsForty patients participated (response = 74%). Twenty-five had not undergone transplantation; 15 had undergone orthotopic liver transplantation. One significant between-group difference was found, namely in substance use and gambling. BA patients who underwent transplantation reported less use than the reference group (p = .01, moderate effect size). Additional moderate effect sizes were found for differences in psychosexual and social development and antisocial behavior. Patients who underwent transplantation had lower scores than one or both other groups.ConclusionsDevelopment of BA survivors who did not undergo transplantation seems not delayed, whereas that of transplanted patients does seem somewhat delayed. However, patients who underwent transplantation display less risk behavior. Larger samples are necessary to confirm these findings.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Adolescent Health - Volume 50, Issue 6, June 2012, Pages 641–644
نویسندگان
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