Real-time PCR hTERT mRNA pattern in tumor core, edge, resection margin, and lymph nodes in laryngeal tumors: Relation to proliferative index and impact on prognosis

hTERT mRNA may potentially be used for molecular reevaluation of the safety margin for conservational laryngeal surgery, and as a prognostic factor for overall survival especially if determined in samples taken from the growing edge of tumors.