Distribution of vascular endothelial growth factor receptor-3/Flt4 mRNA in adult rat central nervous system

► Detailed mapping of VEGFR-3 mRNA expression using in situ hybridization. ► Specific but widespread distribution of VEGFR-3 mRNA in the adult rat CNS. ► Functionally diverse nuclei in the brainstem and spinal cord show hybridization signals. ► Neurosecretory hypothalamic neurons and tanycytes are intensely labeled. ► Circumventricular organs such as the median eminence and area postrema are labeled.