کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1083858 951031 2007 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Implicit self-comparisons against others could bias quality of life assessments
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی سیاست های بهداشت و سلامت عمومی
پیش نمایش صفحه اول مقاله
Implicit self-comparisons against others could bias quality of life assessments
چکیده انگلیسی

ObjectivesTo explore how patient-reported health-related quality of life (HRQL) and global health status are affected by use of differing personal reference frames. We hypothesized that implicit comparisons against self at an earlier time, against healthy peers, or against ill patients would greatly affect patients' response values.Study Design and SettingPatients in a randomized trial for treatment of Paget's disease completed annual HRQL questionnaires. Supplementary questions were appended, asking the patients whether they were aware of having made implicit comparisons.ResultsThe majority of patients reported considering themselves a year ago (31% at baseline), themselves before becoming ill (23%), or other healthy people (24%), with similar proportions during follow-up. Mean HRQL scores varied substantially according to the declared frame of reference, with differences as big as 19% of the scale score, or a standardized mean effect size of 0.74 standard deviations.ConclusionReported reference frames were associated with effects of similar magnitude to the differences in HRQL that are regarded as clinically important. This may be of particular concern in trials that randomize patients to management in different settings, such as treatment at home/in hospital, or surgery/chemotherapy and might bias or obscure HRQL differences.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Epidemiology - Volume 60, Issue 10, October 2007, Pages 1034–1039
نویسندگان
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