کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10871076 | 1074033 | 2013 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Optical manipulation of Saccharomyces cerevisiae cells reveals that green light protection against UV irradiation is favored by low Ca2+ and requires intact UPR pathway
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
YPdDTTEGTART-PCRONPGUPRtunicamycinO-nitrophenyl-β-D-galactopyranoside - O-nitrofenyl-β-D galactopyranosidereverse transcriptase-PCR - RT-PCR معکوسethylene glycol-bis(2-aminoethylether)-N,N,N′,N′-tetraacetic acid - اتیلن گلیکول بیست (2-aminoethylether) -N، N، N '، N'-tetraacetic acidBAPTA - بیایپیتیایOptical manipulation - دستکاری نوریdithiothreitol - دیتیوتریتولSaccharomyces cerevisiae - ساکارومایسس سرویزیهendoplasmic reticulum - شبکه آندوپلاسمی Blue light - نور آبیMiller units - واحدهای میلرUnfolded protein response - پاسخ پروتئین آشکارGreen light - چراغ سبزCalcium - کلسیم
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
دانش گیاه شناسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Optical manipulation of Saccharomyces cerevisiae cells reveals that green light protection against UV irradiation is favored by low Ca2+ and requires intact UPR pathway Optical manipulation of Saccharomyces cerevisiae cells reveals that green light protection against UV irradiation is favored by low Ca2+ and requires intact UPR pathway](/preview/png/10871076.png)
چکیده انگلیسی
Optical manipulation of Saccharomyces cerevisiae cells with high density green photons conferred protection against the deleterious effects of UV radiation. Combining chemical screening with UV irradiation of yeast cells, it was noted that the high density green photons relied on the presence of intact unfolded protein response (UPR) pathway to exert their protective effect and that the low Ca2+ conditions boosted the effect. UPR chemical inducers tunicamycin, dithiotreitol and calcium chelators augmented the green light effect in a synergic action against UV-induced damage. Photo-manipulation of cells was a critical factor since the maximum protection was achieved only when cells were pre-exposed to green light.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEBS Letters - Volume 587, Issue 21, 1 November 2013, Pages 3514-3521
Journal: FEBS Letters - Volume 587, Issue 21, 1 November 2013, Pages 3514-3521
نویسندگان
Ileana C. Farcasanu, Radu Mitrica, Ligia Cristache, Ioana Nicolau, Lavinia L. Ruta, Liliana Paslaru, Sorin Comorosan,