Down-regulated miR-625 suppresses invasion and metastasis of gastric cancer by targeting ILK

► miR-625 is downregulated in gastric cancer. ► miR-625 impaired metastasis in vitro and in vivo. ► miR-625 directly inhibits the protein expression of ILK. ► Si-ILK has a phenocopy of ectopic miR-625. ► miR-625 correlates negatively with ILK.