miR-198 inhibits migration and invasion of hepatocellular carcinoma cells by targeting the HGF/c-MET pathway

► miR-198 directly targets c-MET via its 3′UTR. ► miR-198 expression reduced c-MET expression and HGF induced p44/42 MAPK activation. ► miR-198 expression inhibited HGF promotion of HCC cell migration and invasion.