High-content analysis for drug delivery and nanoparticle applications

- High content analysis (HCA) gives fluorescent imaging data on cell parameters in live cells.
- HCA is now used in to monitor sub-lethal cellular toxicology of drug delivery vehicles.
- Data on permeation enhancers, polymers and nanoparticles is reviewed.
- The data yields quantitative detailed information from up to 72 hour cell exposures.
- HCA also tracks nanoparticle intracellular routing in cells and siRNA can dissect pathways.