Global gene expression and functional network analysis of gastric cancer identify extended pathway maps and GPRC5A as a potential biomarker

► GPRC5A was significantly elevated in gastric cancer tissues. ► The integrative network analysis of deregulated genes generated eight subnetworks. ► WNT, RTK-Ras-PI3K-AKT, NF-κB, PLAU-JAK-STAT pathways showed changes in gene level.