کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10911450 | 1088309 | 2011 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fifth Educational Symposium of the Spanish Lung Cancer Group: Report on the Molecular Biology Workshop
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
تحقیقات سرطان
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The majority of non-small-cell lung cancer (NSCLC) patients present with locally advanced (35%) or metastatic disease (40%); in this setting, it is of the utmost importance to balance efficacy with toxicity. However, with platinum combinations, survival has reached a “plateau”, with median overall survival times of a mere 10-12 months, making it mandatory to search for new strategies and to identify more effective treatment. Molecular characteristics can be more informative than clinical features in predicting clinical benefit, and the identification of molecular markers can help define subgroups of patients who are likely to respond to different treatments, thus avoiding unnecessary toxicities and costs and providing the maximum benefit to each patient. Here we review research on biomarker assessment that was presented during the Molecular Biology Workshop held in Palma de Mallorca on 25 November 2010, during the Fifth Educational Symposium of the Spanish Lung Cancer Group.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Lung Cancer - Volume 74, Issue 3, December 2011, Pages 535-543
Journal: Lung Cancer - Volume 74, Issue 3, December 2011, Pages 535-543
نویسندگان
Isabel Bover, Christian Rolfo, Eloisa Jantus-Lewintre, Rafael Sirera, Carlos Camps, Imane Chaib, Jose L. Ramirez-Serrano, Susana Benlloch, Miguel Angel Molina-Vila, Sara Simonetti, Carlota Costa, Ana Gimenez-Capitan, Pedro Mendez, Miguel Taron,