The effect of glycyrrhizin on maturation and T cell stimulating activity of dendritic cells

► Glycyrrhizin (GL) up-regulates the expression of maturation markers on DCs. ► Treatment of DCs with GL enhances allogenic T cells proliferation. ► Treatment of DCs with GL increases IFN-γ and IL-10 and reduces IL-4 production. ► GL conducts immune responses toward a T helper 1 response.