Influence of TRAF1/C5 and STAT4 genes polymorphisms on susceptibility and severity of rheumatoid arthritis in Egyptian population

► The TRAF1/C5 A allele was significantly associated with RA in Egyptian population. ► The STAT4 T allele was significantly associated with RA in Egyptian population. ► TRAF1/C5 A allele was significantly associated RA severity. ► STAT4 TT genotype was significantly associated RA severity.