کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10931192 1093621 2016 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Centroacinar cells: At the center of pancreas regeneration
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Centroacinar cells: At the center of pancreas regeneration
چکیده انگلیسی
The process of regeneration serves to heal injury by replacing missing cells. Understanding regeneration can help us replace cell populations lost during disease, such as the insulin-producing β cells lost in diabetic patients. Centroacinar cells (CACs) are a specialized ductal pancreatic cell type that act as progenitors to replace β cells in the zebrafish. However, whether CACs contribute to β-cell regeneration in adult mammals remains controversial. Here we review the current understanding of the role of CACs as endocrine progenitors during regeneration in zebrafish and mammals.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Developmental Biology - Volume 413, Issue 1, 1 May 2016, Pages 8-15
نویسندگان
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