Stem cell dynamics in sebaceous gland morphogenesis in mouse skin

► Spatio-temporal organisation of diverse stem cell compartments is highly dynamic. ► Close interrelationship between different stem cell pools during development. ► Regional specificity for patterning of the pilosebaceous unit in mammalian skin. ► Lrig1 positive hair follicle stem cells drive sebaceous gland formation. ► Stem cells essential in adult tissues are also crucial for morphogenesis.