Pitx2c modulates Pax3+/Pax7+ cell populations and regulates Pax3 expression by repressing miR27 expression during myogenesis

► Pitx2c has a role balancing Pax3+/Pax7+ cell populations during myogenesis. ► Only Pitx2c but not Pitx3 modulates cell proliferation and Pax genes expression. ► Pitx2c regulates Pax3 acting by repressing miR-27.