Bi-polarized translation of ascidian maternal mRNA determinant pem-1 associated with regulators of the translation machinery on cortical Endoplasmic Reticulum (cER)

► Translation of cortical pem-1 maternal determinant RNA follows its bi-polarized relocalization ► Maternal determinant RNAs co-localize with phospho-protein regulators of translation initiation ► Localized translation of pem-1 RNA determinant is triggered by the fertilization/calcium wave. ► Phospho-protein regulators of translation initiation co-localize with maternal RNA determinants on a sub-domain of the cortical Endoplasmic Reticulum.