Phosphoribosylamidotransferase, the first enzyme for purine de novo synthesis, is required for conidiation in the sclerotial mycoparasite Coniothyrium minitans

► A gene encoding phosphoribosylamidotransferase was disrupted by T-DNA insertion in a conidiation-deficient mutant of Coniothyrium minitans. ► C. minitans requires more adenosine during conidiation than hyphal growth. ► Phosphoribosylamidotransferase is essential for conidiation of C. minitans via adenosine related molecules.