کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10940902 1095530 2013 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Activation of IL-1β and TNFα genes is mediated by the establishment of permissive chromatin structures during monopoiesis
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Activation of IL-1β and TNFα genes is mediated by the establishment of permissive chromatin structures during monopoiesis
چکیده انگلیسی
The ability to express IL-1β and TNFα is linked to a cell type specific promoter structure, which is established during monocytic but not granulocytic differentiation. The participation of acetylation in IL-1β and TNFα promoter activation shed new light on the regulation of IL-1β or TNFα expression. These data may have implications for understanding the progression from normal to disease conditions.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Immunobiology - Volume 218, Issue 6, June 2013, Pages 860-868
نویسندگان
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