Tapping the brake on cardiac growth-endogenous repressors of hypertrophic signaling-

► Endogenous repressors of cardiac hypertrophy receive less attention than inducers. ► The number of repressors has grown rapidly in the last few years. ► Repressors counterbalance prohypertrophic signaling or transcription. ► Understanding inhibitory pathways may provide valuable therapeutic options for heart disease.