Human progenitor cells derived from cardiac adipose tissue ameliorate myocardial infarction in rodents

► A dimer of the N-terminal domain of RFX5 forms the binding site for RFXAP. ► Multiple contacts from RFX5 promote folding of the C-terminal domain of RFXAP. ► A leucine-rich region of RFX5 is required for dimerization and complex formation. ► Folding of RFXAP results in the formation of a potential binding site for RFXB.