Polymorphisms in the vitamin D receptor gene and type 1 diabetes mellitus risk: An update by meta-analysis

► This is the most comprehensive genetic meta-analysis on polymorphisms in VDR gene and T1DM risk. ► BsmI polymorphism is associated with increased T1DM risks, especially in Asians. ► FokI, ApaI and TaqI polymorphisms are not associated with T1DM risks. ► More studies with larger groups of patients and controls will be required.