کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10958125 1099973 2012 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Attenuation of NF-κβ mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی بیولوژی سلول
پیش نمایش صفحه اول مقاله
Attenuation of NF-κβ mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol
چکیده انگلیسی
► Ethanol-exposed pups showed significant memory impairment in both MWM and EPM. ► Acetylcholinesterase activity and inflammatory markers were significantly enhanced. ► NF-κβ and Caspase-3 activity was also markedly increased in different brain regions. ► Tocotrienol significantly attenuated cognitive deficits in ethanol-exposed pups. ► Neuroinflammtory signaling and neuronal apoptosis was also significantly decreased.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurochemistry International - Volume 61, Issue 3, August 2012, Pages 310-320
نویسندگان
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