Attenuation of NF-κβ mediated apoptotic signaling by tocotrienol ameliorates cognitive deficits in rats postnatally exposed to ethanol

► Ethanol-exposed pups showed significant memory impairment in both MWM and EPM. ► Acetylcholinesterase activity and inflammatory markers were significantly enhanced. ► NF-κβ and Caspase-3 activity was also markedly increased in different brain regions. ► Tocotrienol significantly attenuated cognitive deficits in ethanol-exposed pups. ► Neuroinflammtory signaling and neuronal apoptosis was also significantly decreased.