2-Phenylethynyl-butyltellurium improves memory in mice

► PEBT improves acquisition, consolidation and retrieval on inhibitory avoidance task. ► No differences in the locomotor activity were observed in the open-field test. ► PEBT inhibits glutamate uptake by cerebral cortex and hippocampal slices of mice. ► The improvement of memory by PEBT seems to interact with the glutamatergic system.