Rat brain slices oxidize glucose at high rates: A 13C NMR study

► Innovative approach using cellular metabolomics with carbon 13 NMR. ► Panoramic view of the metabolic fate of glucose and lactate in brain slices. ► Measurement of metabolic fluxes through mathematical modeling of metabolic pathways. ► Use of a cellular model retaining the cell-cell interactions and the in vivo metabolic properties.