Calcium signaling in developing embryos: Focus on the regulation of cell shape changes and collective movements

► Calcium signaling regulates cell rearrangements during convergence extension, epiboly and somitogenesis. ► High calcium accelerates morphogenesis in vivo while low arrest it. ► Calcium spikes induce cells elongation and polarity in embryo. ► Calcium activates assembly of contractile cytoskeleton structures in cells during development.