14-3-3 Proteins: Diverse functions in cell proliferation and cancer progression

► Function and regulation of 14-3-3 binding interactions in RTK/Ras signaling. ► New regulators of 14-3-3 binding interactions in the Hippo pathway. ► 14-3-3 and cell migration: role in regulating the actin cytoskeleton. ► 14-3-3 and EMT: implications for cancer progression. ► 14-3-3 proteins: clinical significance in human cancer.