A family of variable immunoglobulin and lectin domain containing molecules in the snail Biomphalaria glabrata

- Optimized de novo transcriptome assembly allows the study of highly diversified molecules.
- We increased over two fold the number of bonafide FREP gene subfamilies.
- FREP12 are constitutively highly diversified.
- C-type lectin-related proteins (CREPs) combine an IgSF domain with a C-type lectin domain.
- Galectin-related protein (GREP) combines two IgSF domains with a Galectin domain.
- FREPs, CREPs and GREP constitute the VIgL family.