First evidence of protein G-binding protein in the most primitive vertebrate: Serum lectin from lamprey (Lampetra japonica)

- The first to report a novel protein G-binding protein (NPGBP) contained in the lamprey liver.
- Cloned the full-length cDNA of NPGBP gene and production of the recombinant protein and the polyclonal antiserum.
- NPGBP and mammalian Ig molecules combination with protein G in competitive mechanism.
- NPGBP showed agglutination activity against the pathogenic microorganism and promote endothelial cell mitosis.