Molecular cloning and characterization of a C-type lectin in roughskin sculpin (Trachidermus fasciatus)

► TfCTL1 was obviously up-regulated in the skin, blood, spleen and heart. ► TfCTL1 CRD was able to agglutinate some bacteria and a yeast. ► TfCTL1 could bind to several kinds of microorganisms selectively. ► TfCTL1 may play roles in the roughskin sculpin immune response.