Isolation and characterization of homologous TRBP cDNA for RNA interference in Penaeus monodon

► Isolate and characterize the transactivation response RNA binding protein (designated as PmTRBP1). ► PmTRBP1 was elicited by systemic injection of bacterium and virus. ► PmTRBP1 remarkably induced by viral nucleotide analogs. ► PmTRBP1 might function in tiger prawn antibacterial and antiviral response.