کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10973796 | 1108018 | 2016 | 16 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of feeding whole compared with cell-free colostrum on calf immune status: Vaccination response
ترجمه فارسی عنوان
اثر کل تغذیه در مقایسه با کلستروم بدون سلول بر وضعیت ایمنی گوساله: واکنش واکسیناسیون
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کلمات کلیدی
چای سبز انتقال پذیرنده، لکوسیت ها، واکسیناسیون، گوساله لبنی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
Vaccination contributes to improved herd health and production. Boosting immune development at a young age may have long-term effects by enhancing vaccine immune response and efficacy. In the bovine, colostrum is the sole source of maternal immunity, having a substantial effect on health status in the neonate. To date, colostral antibody concentration is used to evaluate colostrum quality. However, colostrum also contains proteins and cells, which may affect immune development and future responses to vaccines. To determine the effect of maternal colostral cells on immune development, 37 female Holstein and Jersey dairy calves were bottle-fed 4 quarts total of whole colostrum (WC) or cell-free colostrum (CFC) at birth. Calves were vaccinated with 2 series of multivalent vaccines. Series A consisted of vaccines given between 1 and 4Â mo of life. Series B consisted of vaccines given between 5 and 10Â mo of life. Calf peripheral blood samples were obtained before each vaccination series and monthly for 3Â mo after each vaccination series. Cellular blood parameters were determined by flow cytometry. Quantitative real-time PCR was used to determine cytokine gene expression in peripheral blood mononuclear cells before vaccination series B and once a month for 2Â mo after vaccination series B. Calves fed CFC had fewer numbers of B cells in mo 2 after vaccination series A when compared with WC-fed calves. Calves fed CFC had decreased gene expression levels of IL-2 in mo 1 and numbers of CD4+CD62L+CD45ROâ and CD4+CD62L+CD45RO+ T cells in mo 0 and 1 after vaccination series B as compared with WC-fed calves. Our findings indicate a greater response to vaccines up to 6 to 10Â mo post-WC feeding when compared with CFC. These data suggest that adoptive transfer of maternal colostral cells at birth has a long-term effect on development of the neonatal immune system.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Dairy Science - Volume 99, Issue 5, May 2016, Pages 3979-3994
Journal: Journal of Dairy Science - Volume 99, Issue 5, May 2016, Pages 3979-3994
نویسندگان
S.N. Langel, W.A. Wark, S.N. Garst, R.E. James, M.L. McGilliard, C.S. Petersson-Wolfe, I. Kanevsky-Mullarky,