کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10975478 | 1108034 | 2015 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Pulsed electric field processing preserves the antiproliferative activity of the milk fat globule membrane on colon carcinoma cells
ترجمه فارسی عنوان
پردازش میدان الکترومغناطیسی، فعالیت ضد انعقادی غشای چربی شیر را در سلول های کارسینومای کولون حفظ می کند
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کلمات کلیدی
غشای غلیظ چربی شیر، میدان الکتریکی پالس، فعالیت ضد انعقادی،
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
The present work evaluated the effect of processing on the antiproliferative activities of milk fat globule membrane (MFGM) extracts. The antiproliferative activity on human adenocarcinoma HT-29 cells of untreated MFGM extracts were compared with those extracted from pasteurized cream, thermally treated cream, or cream subjected to pulsed electrical field (PEF) processing. The PEF with a 37 kV/cm field strength applied for 1,705 μs at 50 and 65°C was applied to untreated cream collected from a local dairy. Heating at 50 or 65°C for 3 min (the passage time in the PEF chamber) was also tested to evaluate the heating effect during PEF treatments. The MFGM extracted from pasteurized cream did not show an antiproliferative activity. On the other hand, isolates from PEF-treated cream showed activity similar to that of untreated samples. It was also shown that PEF induced interactions between β-lactoglobulin and MFGM proteins at 65°C, whereas the phospholipid composition remained unaltered. This work demonstrates the potential of PEF not only a means to produce a microbiologically safe product, but also as a process preserving the biofunctionality of the MFGM.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Dairy Science - Volume 98, Issue 5, May 2015, Pages 2867-2874
Journal: Journal of Dairy Science - Volume 98, Issue 5, May 2015, Pages 2867-2874
نویسندگان
S. Xu, M. Walkling-Ribeiro, M.W. Griffiths, M. Corredig,