Acquired factor V inhibitor-related severe bleeding due to unformed prothrombinase complex

- Patient's FV inhibitor was of an IgG class that recognized both the heavy and light chains of FV.
- Patient's FV inhibitor inhibits the FVa-FXa binding, and FV-phospholipid binding.
- In this case, it is thought that the immune response occurred by using fibrin glue 13 years ago.