کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
11009521 | 1826478 | 2018 | 7 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Meningioma in the elderly: Characteristics, prognostic factors, and surgical strategy
ترجمه فارسی عنوان
مننژیوم در سالمندان: ویژگی ها، عوامل پیش آگهی شده و استراتژی جراحی
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کلمات کلیدی
CTAGSSMRAGOSCCICMHKPSComputed tomography angiography - آنژیوگرافی توموگرافیک کامپیوتریMagnetic resonance angiography - آنژیوگرافی رزونانس مغناطیسیMRI - امآرآی یا تصویرسازی تشدید مغناطیسیMagnetic resonance imaging - تصویربرداری رزونانس مغناطیسیNeurosurgery - جراحی مغز و اعصابCNS - دستگاه عصبی مرکزیWorld Health Organization - سازمان بهداشت جهانیCharlson Comorbidity Index - شاخص همجواری چارلزونAged - مسنKarnofsky performance scale - مقیاس عملکرد KarnofskyGlasgow Outcome Scale - مقیاس نتیجه گلاسکوMeningioma - مننژیومTreatment outcome - نتیجه درمانWHO - که
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
عصب شناسی
چکیده انگلیسی
Meningioma is one of the most common intracranial tumors. It has the features of benign and slow growing. We focused on the meningioma in the elderly, retrospectively analyzed 528 valid meningioma patients, including 115 (21.8%) patients older than 65â¯years old. The elderly patients were shown to have significantly larger tumor diameter (mean [±SD] 43.4â¯Â±â¯18.0â¯mm) comparing with the young group (mean [±SD] 37.6â¯Â±â¯16.5â¯mm, pâ¯<â¯0.01). Post-operative KPS was significantly lower in the elderly group (mean [±SD] 79.64â¯Â±â¯26.37) than the young group (mean [±SD] 88.81â¯Â±â¯17.36, pâ¯<â¯0.01). Multivariate regression of post-operative KPS scales at discharge and 6â¯months follow-up showed operative complications, pre-operative comorbidities, tumor diameter, and challenging location had a significant impact on the outcome. However, tumor blood supply, Simpson grades, pathology, and pre-operative symptoms were shown to have less impact on the post-operative KPS scale. The outcome for meningioma in elderly patients was affected by factors related more to the safety of the operation than characteristics of the tumor. Therefore, rather than achieving total resection, conservative and safety preferential treatment strategies should be regarded as a higher priority for better quality of life.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Clinical Neuroscience - Volume 56, October 2018, Pages 143-149
Journal: Journal of Clinical Neuroscience - Volume 56, October 2018, Pages 143-149
نویسندگان
Xiaochun Zhao, Dongxu Zhao, Yuxin Wu, Weizhen Gao, Hua Cui, Yong Wang, Peter Nakaji, Yinghui Bao,