Systematic review of acute pancreatitis associated with interferon-α or pegylated interferon-α: Possible or definitive causation?

AP-IFN is rare and has a probable or definite causal relation according to Naranjo scale. The evidence supports a class Ia of Badalov classification. Hypertriglyceridemia is not a contributing factor. IFN-induced AP is usually mild or moderately severe, and responds favorably to supportive management.