کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
11019420 1718107 2019 23 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Influence of bacteriophages cocktail on European eel (Anguilla anguilla) immunity and survival after experimental challenge
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم آبزیان
پیش نمایش صفحه اول مقاله
Influence of bacteriophages cocktail on European eel (Anguilla anguilla) immunity and survival after experimental challenge
چکیده انگلیسی
Inland fishery belongs to those branches of animal production that use very large amounts of chemotherapeutics, in particular antibiotics. The accumulation of chemotherapeutic agents in bottom sediments is a direct threat to the aquatic environment and directly affects the condition and health of the fish. Finding a preparation that could be used both prophylactically to increase the resistance of fish and therapeutically in case of infection with pathogenic bacteria, without side effects for fish and aquatic environment could be a great solution to this problem. Our aim was to determine influence of BAFADOR® the new bacteriophage-based preparation on European eel immunity and survival after experimental challenge. Application of BAFADOR® increased total protein level, immunoglobulin level, lysozyme activity and ceruloplasmin level in European eel serum. Potential killing activity and metabolic activity of spleen phagocytes as well as pronephros lymphocyte proliferation of was higher compared to control. The preparation also reduced mortality after experimental infections with the pathogenic bacteria Aeromonas hydrophila and Pseudomonas fluorescens. Our results showed that preparation BAFADOR® is well tolerated by the fish organism causing stimulation of cellular and humoral immunity parameters and reduces the mortality of the European eel after experimental challenge.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fish & Shellfish Immunology - Volume 84, January 2019, Pages 28-37
نویسندگان
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