Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity

Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Medicinal Chemistry - Volume 158, 5 October 2018, Pages 832-852

Tetsuya Iida, Minoru Ubukata, Ikuo Mitani, Yuichi Nakagawa, Katsuya Maeda, Hiroto Imai, Yosuke Ogoshi, Takahiro Hotta, Shohei Sakata, Ryuhei Sano, Hisayo Morinaga, Tamotsu Negoro, Shinichi Oshida, Masahiro Tanaka, Takashi Inaba,