Keywords: استارویل-کاپا دساتوراز 1; GDM; gestational diabetes mellitus; T2D; type 2 diabetes; CVD; cardiovascular disease; DOHaD; developmental origins of health and disease; CDA; Canadian diabetes association; HOMA-IR; homeostatic model assessment for insulin resistance; DINT; dietary inte
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Keywords: استارویل-کاپا دساتوراز 1; Plin; perilipin; PPAR; peroxisome proliferator-activated receptor; SREBP1c; sterol regulatory element-binding transcription factor 1c; ChREBP; carbohydrate response element binding protein; SCD1; stearoyl-CoA desaturase 1; ACSL1; long-chain acyl-CoA synth
Keywords: استارویل-کاپا دساتوراز 1; AD; Alzheimer's disease; PD; Parkinson's disease; SPT; serine palmitoyltransferase; TFA; trifluoroacetic acid; LC/MS; liquid chromatography/mass spectrometry; UPLC; ultra-performance liquid chromatography; TQ-MS; triple quadrupole mass spectrometer; ESI;
Keywords: استارویل-کاپا دساتوراز 1; Myo-inositol; Lipotrope; High-fructose diet; Fatty liver; Fructolysis/lipogenesis; ACACA; acetyl-CoA carboxylase alpha; ACS; acyl-CoA synthetase; ALDOB; aldolase B; ChREBP; carbohydrate-responsive element-binding protein; CPT1a; carnitine palmitoyltransfe
Keywords: استارویل-کاپا دساتوراز 1; ALT; alanine aminotransferase; CPT1; carnitine palmitoyltransferase 1; DAG; diacylglycerol; DNL; de novo lipogenesis; FAS; fatty acid synthase; FFA; free fatty acid; GC-MS; gas chromatography-mass spectrometry; MCD; methionine-choline-deficient; MIDA; mas
Keywords: استارویل-کاپا دساتوراز 1; Acox; acyl-CoA oxidase; Agpat; acylglycerol-3-phosphate-O-acyltransferase; aP2; adipose fatty acid binding protein; Atgl; adipose triglyceride lipase; AUC; area under the curve; B. wadsworthia; Bilophila wadsworthia; Cd36; cluster of differentiation 36; C
Keywords: استارویل-کاپا دساتوراز 1; ACOX; peroxisomal acyl-coenzyme A oxidase 1; BDNF; Brain-derived neurotrophic factor; BM; bardoxolone methyl; CDDO-Im; 1-[2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oyl]imidazole; FAS; fatty acid synthase; FOXO1; Forkhead box protein O1; HF; high fat; LC; l
Keywords: استارویل-کاپا دساتوراز 1; Ovariectomy; Hyperphagia; Triacylglycerol; Liver; Plasma; Desaturase; OVX + AL; ovariectomized rat with ad libitum access to food; OVX + PF; ovariectomized rat pair-fed to sham-operated rat; SHAM; sham-operated rat; VO2; volume of oxygen consumed; VCO2; v
Keywords: استارویل-کاپا دساتوراز 1; ACC; acetyl-CoA carboxylase; ACL; ATP-citrate lyase; AMPK; 5â²-AMP-dependent protein kinase; Apc; adenomatous polyposis coli; BMAL1; brain and muscle Arnt-like 1; CCG; clock controlled genes; CLOCK; circadian locomotor output cycles kaput; CPT1/CPT2; car
Keywords: استارویل-کاپا دساتوراز 1; ABCA1; ATP-binding cassette sub-family A member 1; AD; Alzheimer's disease; apoB48; apolipoprotein B-48; APP; amyloid precursor protein; BCMO1; β-carotene 15,15â²-monooxygenase; BLAOA; bovine α-lactalbumin complexed with oleic acid; CD36; cluster of di
Keywords: استارویل-کاپا دساتوراز 1; ATIC; allylisothiocyanate; GLUT4; glucose transporter 4; mtDNA; mitochondrial DNA; FFA; free fatty acid; OCR; Oxygen consumption rate; DMEM; Dulbecco's Modified Eagle's medium; FBS; fetal bovine serum; 2-NBDG; 2-[N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl) amin
Keywords: استارویل-کاپا دساتوراز 1; AEBS; antiestrogen binding site; ChEH; cholesterol epoxide hydrolase; Tam; tamoxifen, trans-2-[4-(1,2-diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine; 4OH-tam; 4-[(Z)-1-[4-(2-dimethylaminoethyloxy)phenyl]-2-phenylbut-1-enyl]phenol; Ralox; raloxifene, [
Discovery of potent liver-selective stearoyl-CoA desaturase-1 (SCD1) inhibitors, thiazole-4-acetic acid derivatives, for the treatment of diabetes, hepatic steatosis, and obesity
Keywords: استارویل-کاپا دساتوراز 1; Stearoyl-CoA desaturase 1; Liver-selective SCD1 inhibitor; Thiazole-4-acetic acid derivative; Physicochemical properties;
Vitamin A deficiency induces endoplasmic reticulum stress and apoptosis in pancreatic islet cells: Implications of stearoyl-CoA desaturase 1-mediated oleic acid synthesis
Keywords: استارویل-کاپا دساتوراز 1; CHOP; CCAAT/Enhancer-binding protein homologues protein; D9D; Delta-9 desaturase; DHA; Docosahexaenoic acid; ER; Endoplasmic reticulum; eNOS; Endothelial nitric oxide synthase; HFr; High fructose; MUFA; Monounsaturated fatty acid; NAFLD; Non-alcoholic fat
The influence of peroxisome proliferator-activated receptor γ (PPARγ) ligands on cancer cell tumorigenicity
Keywords: استارویل-کاپا دساتوراز 1; Cancer cells; PPARγ agonist; PPARγ antagonist; Therapeutic agents; Tumorigenicity; ACC; Acetyl-CoA carboxylase; AKR1B10; Alde-keto reductase 1B10; Alpha-ESA; Alpha-eleostreac acid; ACLY; ATP citrate lyase; BADGE; Bisphenol-A-diglycidyl-etter; CSCs; Canc
Lipid droplets induced by secreted phospholipase A2 and unsaturated fatty acids protect breast cancer cells from nutrient and lipotoxic stress
Keywords: استارویل-کاپا دساتوراز 1; AA; arachidonic acid; AMPK; AMP-dependent protein kinase; ATGL; adipose triglyceride lipase; cPLA2α; cytosolic group IVA PLA2; CPT1; carnitine O-palmitoyltransferase 1; CPT1A; the liver isoform of CPT1; DGAT1; diacylglycerol acyltransferase 1; DHA; docos
In vitro and in vivo antitumor activities of T-3764518, a novel and orally available small molecule stearoyl-CoA desaturase 1 inhibitor
Keywords: استارویل-کاپا دساتوراز 1; Lipogenesis; Stearoyl-CoA desaturase 1; Saturated fatty acids; Phosphatidylcholine; Endoplasmic reticulum stress; Cancer;
Effect of Gangjihwan on hepatic steatosis and inflammation in high fat diet-fed mice
Keywords: استارویل-کاپا دساتوراز 1; ACC1; acetyl-CoA carboxylase 1; ACOX; fatty acyl-CoA oxidase; ALT; alanine transaminase; C/EBPα; CCAAT/enhancer binding protein α; CPT-1; carnitine palmitoyltransferase I; DF; Gangjihwan; FAS; fatty acid synthase; HE; hematoxylin-eosin; HFD; high fat di
Synthesis of the suspected trans-11,cis-13 conjugated linoleic acid isomer in ruminant mammary tissue by FADS3-catalyzed Î13-desaturation of vaccenic acid
Keywords: استارویل-کاپا دساتوراز 1; vaccenic acid; trans-11,cis-13 conjugated linoleic acid; fatty acid desaturase 3; stearoyl-CoA desaturase 1;
BNIP3 induction by hypoxia stimulates FASN-dependent free fatty acid production enhancing therapeutic potential of umbilical cord blood-derived human mesenchymal stem cells
Keywords: استارویل-کاپا دساتوراز 1; Annexin V; FITC-conjugated annexinV; BCA; bicinchoninic acid; BNIP3; Bcl2/adenovirus E1B 19Â kDa protein-interacting protein 3; CBP; CREB-binding protein; CCCP; carbonyl cyanide m-chlorophenyl hydrazine; CHIP; chromatin immunoprecipitation; CHOP; CCAAT-en
Protective effects of gomisin N against hepatic steatosis through AMPK activation
Keywords: استارویل-کاپا دساتوراز 1; Gomisin N; Nonalcoholic fatty liver disease; Lipogenesis; AMP-activated protein kinase; Sterol regulatory element-binding protein 1c; High-fat diet; ACC; Acetyl-CoA carboxylase; AMPK; Adenosine monophosphate (AMP)-activated protein kinase; CPT 1; Carnitin
Hair Growth Cycle Is Arrested in SCD1 Deficiency by Impaired Wnt3a-Palmitoleoylation and Retrieved by the Artificial Lipid Barrier
Keywords: استارویل-کاپا دساتوراز 1; IFE; interfollicular epidermis; SCD1; stearoyl-CoA desaturase 1; TEWL; transepidermal water loss; WAT; white adipose tissue;
Ageing sensitized by iPLA2β deficiency induces liver fibrosis and intestinal atrophy involving suppression of homeostatic genes and alteration of intestinal lipids and bile acids
Keywords: استارویل-کاپا دساتوراز 1; ACC; acetyl-CoA carboxylase; ATF6; activating transcription factor6; AB-PAS; alcian blue-periodic acidschiff; ACC; acetyl-CoA carboxylase; ACSL; long-chain acyl-CoA synthetase; Bad; Bcl-2-associated death promoter; Bax; Bcl-2-like protein 4; Bcl-2; B-cell
Fibroblast growth factor 21 (FGF21) is robustly induced by ethanol and has a protective role in ethanol associated liver injury
Keywords: استارویل-کاپا دساتوراز 1; Binge ethanol consumption; FGF21; Chronic ethanol consumption; Alcoholic liver disease; ACSS2; acyl-coenzyme a synthetase short-chain family member 2; ADH 1 and 2; alcohol dehydrogenase 1 and 2; ALDH1α1; aldehyde dehydrogenase 1 alpha 1; ALD; alcoholic l
Daidzein reduces the proliferation and adiposeness of 3T3-L1 preadipocytes via regulating adipogenic gene expression
Keywords: استارویل-کاپا دساتوراز 1; Daidzein; 3T3-L1 preadipocytes; Proliferation; Adipogenesis; Arachidonic acid (PubChem CID: 444899); Daidzein (PubChem CID: 5281708); Dexamethasone (PubChem CID: 5743); Dimethyl sulfoxide (PubChem CID: 679); Isopropanol (PubChem CID: 3776); Oil Red O (Pub
Liver X receptor α promotes the synthesis of monounsaturated fatty acids in goat mammary epithelial cells via the control of stearoyl-coenzyme A desaturase 1 in an SREBP-1-dependent manner
Keywords: استارویل-کاپا دساتوراز 1; stearoyl-CoA desaturase 1; liver X receptor α; monounsaturated fatty acids; transcriptional regulation;
Transcriptional regulation analysis of FAM3A gene and its effect on adipocyte differentiation
Keywords: استارویل-کاپا دساتوراز 1; FAM3A; family with sequence similarity 3, member A; G6PD; glucose-6-phosphate dehydrogenase; PPARG(2); peroxisome proliferator-activated receptor gamma(2); C/EBPα; CCAAT/enhancer binding protein alpha; C/EBPβ(C/EBPβbeta); CCAAT/enhancer binding protein
SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: Effects on cellular stress, inflammatory markers and fatty acid elongation
Keywords: استارویل-کاپا دساتوراز 1; Palmitate; Stearate; Palmitoleate; Oleate; Stearoyl-CoA desaturase 1; SCD1 Inhibitor; Elongase 6;
Fenofibrate insulates diacylglycerol in lipid droplet/ER and preserves insulin signaling transduction in the liver of high fat fed mice
Keywords: استارویل-کاپا دساتوراز 1; DNL; de novo lipogenesis; IRS1; insulin-receptor-substrate 1; FB; fenofibrate; GTT; glucose tolerance test; β-HAD; β3-hydroxyacyl-CoA dehydrogenase; LCACoA; long chain acyl-CoA; DAG; diacylglycerol; GSK3β; glycogen synthase kinase; SREBP-1c; sterol reg
Ï-3 Fatty acids reverse lipotoxity through induction of autophagy in nonalcoholic fatty liver disease
Keywords: استارویل-کاپا دساتوراز 1; Lipotoxicity; Nonalcoholic fatty liver disease; Ï-3 Fatty acids; Autophagy; Stearoyl-CoA desaturase 1;
Three unsaturated fatty acid biosynthesis-related genes in yellow catfish Pelteobagrus fulvidraco: Molecular characterization, tissue expression and transcriptional regulation by leptin
Keywords: استارویل-کاپا دساتوراز 1; ARA; arachidonic acid; BW; body weight; DHA; docosahexaenoic acid; EPA; eicosapentaenoic acid; ELOVL; elongase of very long-chain fatty acid; FAD; fatty acyl desaturase; MUFA; mono-unsaturated fatty acid; PUFA; polyunsaturated fatty acid; rb-hLEP; recombi
The liver-selective NO donor, V-PYRRO/NO, protects against liver steatosis and improves postprandial glucose tolerance in mice fed high fat diet
Keywords: استارویل-کاپا دساتوراز 1; Nitric oxide; Hepatoprotection; Liver steatosis; Glucose tolerance; Fatty acid metabolism; ABCA1; ATP-binding cassette transporter family member 1; ACC; native isoform acetyl-CoA carboxylase; Akt; serine/threonine-protein kinase; ALT; alanine aminotransfe
Identification and expression pattern of two novel alternative splicing variants of EEF1D gene of dairy cattle
Keywords: استارویل-کاپا دساتوراز 1; eEF1; eukaryotic elongation factor 1; eEF1A; eukaryotic elongation factor 1A; eEF1B; eukaryotic elongation factor 1B; eEF1Bγ; eukaryotic elongation factor 1γ; eEF1Bα; eukaryotic elongation factor 1α; eEF1Bδ; eukaryotic elongation factor 1Bδ; EEF1D;
Stearoyl-CoA desaturase regulates inflammatory gene expression by changing DNA methylation level in 3T3 adipocytes
Keywords: استارویل-کاپا دساتوراز 1; SCD1; stearoyl-CoA desaturase 1; WAT; white adipose tissue; TNFα; tumor necrosis factor-α; IL6; interleukin 6; MCP1; monocyte chemoattractant protein 1; LPS; lipopolysaccharide; Il10ra; interleukin 10 receptor a; Il6st; interleukin 6 signal transducer;
Liquid fructose downregulates Sirt1 expression and activity and impairs the oxidation of fatty acids in rat and human liver cells
Keywords: استارویل-کاپا دساتوراز 1; ACO; acyl-CoA oxydase; AMPK; AMP-activated protein kinase; APRT; adenosyl phosphoribosyl transferase); ACC; acetyl-CoA carboxylase); ChREBP; carbohydrate response element binding protein; CYP4A1; cytochrome P450 4A1; FAS; fatty acid synthase; Foxa2; forkh
Adiponectin activates the AMPK signaling pathway to regulate lipid metabolism in bovine hepatocytes
Keywords: استارویل-کاپا دساتوراز 1; Ad; adiponectin; NEB; negative energy balance; AdipoR1; adiponectin receptor 1; AdipoR2; adiponectin receptor 2; AMPK; AMP-activated protein kinase; PPARα; peroxisome proliferator-activated receptor α; SREBP-1c; sterol regulatory element-binding protein
Suppression of acute ethanol-induced hepatic steatosis by docosahexaenoic acid is associated with downregulation of stearoyl-CoA desaturase 1 and inflammatory cytokines
Keywords: استارویل-کاپا دساتوراز 1; Alcoholic liver disease; Hepatic steatosis; Docosahexaenoic acid; Stearoyl-CoA desaturase 1; Inflammatory cytokines
Polyphenol-rich black chokeberry (Aronia melanocarpa) extract regulates the expression of genes critical for intestinal cholesterol flux in Caco-2 cells
Keywords: استارویل-کاپا دساتوراز 1; ACOX-1; acyl-CoA oxidase 1; ABCA1; ATP binding cassette transporter A1; ABCG5/8; ATP binding cassette transporter G5/8; CVD; cardiovascular disease; CPT-1α; carnitine palmitoyltransferase 1α; FAS; fatty acid synthase; HMGR; 3-hydroxy-3-methylglutaryl co
Increased availability of endogenous and dietary oleic acid contributes to the upregulation of cardiac fatty acid oxidation
Keywords: استارویل-کاپا دساتوراز 1; ACC; acetyl-CoA carboxylase; ACO; acyl-CoA oxidase; ACS; acyl-CoA synthetase; AMPK; AMP-activated protein kinase; CD36; fatty acid translocase/CD36; CPT1; carnitine palmitoyltransferase 1; FA; fatty acids; NEFA; non-esterified FA; FATP1; fatty acid transp
Ethyl 2,4,6-trihydroxybenzoate is an agonistic ligand for liver X receptor that induces cholesterol efflux from macrophages without affecting lipid accumulation in HepG2 cells
Keywords: استارویل-کاپا دساتوراز 1; ABC; ATP-binding cassette transporter; FAS; fatty acid synthase; HDL; high-density lipoprotein; LBD; ligand-binding domain; LDL; low-density lipoprotein; LXR; liver X receptor; NPC1L1; Niemann-Pick C1 Like 1; SCD-1; stearoyl-CoA desaturase 1; SPR; surface
Enzymatic activity and genetic variation in SCD1 modulate the relationship between fatty acids and inflammation
Keywords: استارویل-کاپا دساتوراز 1; BMI; body mass index; CRP; C-Reactive protein; FA; fatty acids; FFQ; food frequency questionnaire; HOMA-IR; homeostasis model of assessment of insulin resistance; HWE; Hardy-Weinberg equilibrium; MAF; minor allele frequency; MUFA; monounsaturated fatty
Palmitic acid follows a different metabolic pathway than oleic acid in human skeletal muscle cells; lower lipolysis rate despite an increased level of adipose triglyceride lipase
Keywords: استارویل-کاپا دساتوراز 1; ASMs; acid soluble metabolites; ACSL; long-chain fatty acyl-CoA synthetase; ATGL; adipose triglyceride lipase; BSA; bovine serum albumin; CA; cell-associated; CD36/FAT; fatty acid translocase; FDR; false discovery rate; CE; cholesteryl ester; CRAT; carnit
Hormonal and nutritional regulation of SCD1 gene expression
Keywords: استارویل-کاپا دساتوراز 1; Stearoyl-Coa desaturase 1; Hormonal regulation; Nutritional regulation; Transcription factorsAA, arachidonic acid; Akt, protein kinase B; AP-1, Activated Protein-1; C/EBP, CCAAT-enhancer-binding protein; ChREBP, Carbohydrates response element binding prot
Mechanisms involved in lipid accumulation and apoptosis induced by 1-nitropyrene in Hepa1c1c7 cells
Keywords: استارویل-کاپا دساتوراز 1; Apoptosis; Cholesterol; Fatty acids; Hepatoma cells; 1-Nitropyrene; Stearoyl-CoA desaturase 1;
Influence of stearoyl-coenzyme A desaturase 1 genotype and stage of lactation on fatty acid composition of Canadian Jersey cows
Keywords: استارویل-کاپا دساتوراز 1; stearoyl-CoA desaturase 1; desaturase index; fatty acid composition; Jersey;
The potential role of green tea catechins in the prevention of the metabolic syndrome - A review
Keywords: استارویل-کاپا دساتوراز 1; BMI; body mass index; COMT; catechol-O-methyl-transferase; EC; (â)-epicatechin; ECG; (â)-epicatechin-3-gallate; EGC; (â)-epigallocatechin; EGCG; (â)-epigallocatechin-3-gallate; HDL; high density lipoprotein; IDF; International Diabetes Federation;