کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1138882 1489198 2008 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Optimal and sub-optimal quarantine and isolation control in SARS epidemics
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی کنترل و سیستم های مهندسی
پیش نمایش صفحه اول مقاله
Optimal and sub-optimal quarantine and isolation control in SARS epidemics
چکیده انگلیسی

This paper discusses the application of optimal and sub-optimal controls to a SEQIJR SARS model via the Pontryagin’s Maximum Principle. To this end, two control variables representing the quarantine and isolation strategies are considered in the model. The numerical optimal control laws are implemented in an iterative method, and the sub-optimal solution is computed using a genetic algorithm. The simulation results demonstrate that the maximal applications of quarantining and isolation strategies in the early stage of the epidemic are of very critical impacts in both cases of optimal and sub-optimal control. Otherwise, the control effect will be much worse. This gives a theoretical interpretation to the practical experiences that the early quarantine and isolation strategies are critically important to control the outbreaks of epidemics. Furthermore, our results also show that the proposed sub-optimal control can lead to performances close to the optimal control, but with much simpler strategies for long periods of time in practical use.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Mathematical and Computer Modelling - Volume 47, Issues 1–2, January 2008, Pages 235–245
نویسندگان
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