An OLS-based predictor test for a single-index model for predicting transcription rate from histone acetylation level

In this work a simultaneous procedure of selection of transcription factor binding motif scores and histone acetylation levels important to the transcription rates of genes is proposed for a single-index model. Multiple simulation studies confirm the theory of the proposed method. The method is illustrated using a real data set for histone acetylation of yeast.