کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1161991 1490532 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Morphogenesis, Dictyostelium, and the search for shared developmental processes
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم کشاورزی و بیولوژیک (عمومی)
پیش نمایش صفحه اول مقاله
Morphogenesis, Dictyostelium, and the search for shared developmental processes
چکیده انگلیسی

In the 1930s John Tyler Bonner began studying the slime mold, Dictyostelium discoideum, as a way to investigate how organisms develop. With a life cycle that includes periods of unicellularity and multicellularity, Dictyostelium raises questions fundamental to development and evolution. In Morphogenesis: An Essay on Development (1952), Bonner built on his work with Dictyostelium to inform developmental theory and practice. By exploring how Bonner’s early work with Dictyostelium motivated his synthetic approach in Morphogenesis, this paper presents an example of how those who studied development sought ways to gain traction in the rapidly changing life sciences. While a biochemical viewpoint of development became dominant, morphogenesis provided a way to reintroduce and emphasize biological organization at the organismal level. Bonner’s early work offers a window to mid-twentieth century studies of development, an understudied area in the history of science, and shows that it was a time when growing experimental evidence enabled new ways of thinking about the relationship between ontogeny and evolution, and more broadly, about how the parts of nature might fit together.


► Explores John Tyler Bonner’s pioneering research (1930s–1940s) on slime molds.
► Provides a window to an understudied area: mid-twentieth century embryology.
► Bonner contributed to the foundation of evolutionary developmental biology.
► Bonner’s early work remains relevant today.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Studies in History and Philosophy of Science Part C: Studies in History and Philosophy of Biological and Biomedical Sciences - Volume 42, Issue 4, December 2011, Pages 508–517
نویسندگان
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